New research indicates that pregnant women with pre-gestational diabetes who take metformin are at a higher risk for adverse pregnancy outcomes—such as major birth defects and pregnancy loss—than the general population, but their increased risk is not due to metformin but diabetes.

The findings come from a British Journal of Clinical Pharmacology study including 471 women in the metformin group and 479 in the reference group.

 

 

Source: Wiley

Full bibliographic information:

Pregnancy outcomes in women on metformin for diabetes or other indications among those seeking teratology information services. British Journal of Clinical Pharmacology.